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Multiple Choice

In a client suspected of having Paget's disease, which laboratory study would the nurse expect to be prescribed?

In Paget's disease, which is a chronic disorder that can result in enlarged and misshapen bones, the laboratory study most pertinent to diagnose and monitor the condition is alkaline phosphatase. This enzyme is found in various tissues throughout the body, with particularly high concentrations in the liver, bones, kidneys, and bile ducts. In individuals with Paget's disease, elevated levels of alkaline phosphatase are indicative of increased bone turnover and can reflect the active remodeling process occurring within the affected bones. Testing for alkaline phosphatase helps in assessing the extent of the disease and monitoring the effectiveness of treatment. Thus, in the context of a client suspected of having Paget's disease, the expectation for an elevated alkaline phosphatase level aligns with the pathophysiology of the disorder, making it the appropriate laboratory study to be prescribed.

In Paget's disease, which is a chronic disorder that can result in enlarged and misshapen bones, the laboratory study most pertinent to diagnose and monitor the condition is alkaline phosphatase. This enzyme is found in various tissues throughout the body, with particularly high concentrations in the liver, bones, kidneys, and bile ducts. In individuals with Paget's disease, elevated levels of alkaline phosphatase are indicative of increased bone turnover and can reflect the active remodeling process occurring within the affected bones.

Testing for alkaline phosphatase helps in assessing the extent of the disease and monitoring the effectiveness of treatment. Thus, in the context of a client suspected of having Paget's disease, the expectation for an elevated alkaline phosphatase level aligns with the pathophysiology of the disorder, making it the appropriate laboratory study to be prescribed.